Effect of Monthly 100,000 IU Vitamin D Supplementation on Falls and Non-Vertebral Fractures

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Vitamin D supplementation and the prevention of fractures and falls.

Vitamin B12 deficiency is common in older people and is associated with cognitive impairment in the absence of anaemia or macrocytosis [1–3]. The prevalence of vitamin B12 deficiency increases in the elderly, mainly due to malabsorption of food-bound vitamin B12 due to atrophic gastritis that limits the ability of older people to release vitamin B12 from dietary sources in meat, fish and dairy ...

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The effect of Vitamin D on falls and fractures.

Vitamin D (cholecalciferol) is important for normal development and maintenance of the skeleton. The metabolites 25(OH)D and 1,25(OH)(2)D are not only important for treating rickets and osteomalacia but also for all types and clinical stages of osteoporosis. Patients with low calcium intake and a low vitamin D status are at risk to develop secondary hyperparathyroidism, increased bone resorbtio...

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Vitamin D supplementation to reduce the risk of falls and fractures: the dosing dilemma.

Many tissues in the body have vitamin D receptors. Maintenance of adequate vitamin D serum levels has been linked to a variety of health benefi ts. Vitamin D defi ciency, defi ned as a serum 25-hydroxyvitamin D level 20 ng/mL, is becoming a common issue as our population ages and sun exposure is minimized. Vitamin D defi ciency can lead to osteoporosis, muscle weakness, and increased risk of fa...

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Serum 25-hydroxyvitamin D response to vitamin D3 supplementation 50,000 IU monthly in youth with HIV-1 infection.

CONTEXT Vitamin D deficiency and insufficiency occur frequently in youth with HIV infection, particularly among those receiving the antiretroviral drug efavirenz. Optimal vitamin D dosing for treatment is unclear. OBJECTIVE Our objective was to evaluate safety and measure change in 25-hydroxyvitamin D (25-OHD) concentration from baseline to study wk 4 and 12 during treatment with vitamin D(3)...

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ژورنال

عنوان ژورنال: Cureus

سال: 2021

ISSN: 2168-8184

DOI: 10.7759/cureus.12445